fensisuperstar Ja ne vidim za sad nikakve konkretne dokaze iz provedenih istraživanja da možemo biti 100% sigurni da paracetamol korišten u nekoj dobi trudnoće ne utječe na razvoj fetusa/bebe i samim time ne uzrokuje autizam.
evo ti jedan
https://pubmed.ncbi.nlm.nih.gov/38592388/
The study led by Ahlqvist harnessed data on nearly 2.5 million children born in Sweden between 1995 and 2019 and — from the country’s extensive health records — data on acetaminophen prescriptions during pregnancy and on self-reported use collected by midwives, as well as whether children later received autism diagnoses.
The study showed that around 1.42% of children exposed to acetaminophen during pregnancy were autistic, compared to 1.33% of children who were not exposed ─ a “very small” difference, says Ahlqvist.
The team also compared pairs of siblings (born to the same mother), one of whom had been exposed to acetaminophen and one who had not. Siblings share half of their genome, and share a similar upbringing and mother’s background health, so any detected difference in autism between siblings is more likely to be due to the drug. The researchers found no association between acetaminophen and autism using this method — which supports the idea that links found in other studies were really explained by confounding factors.
Working out whether there is a link between the drug and autism is difficult, says Viktor Ahlqvist, an epidemiologist at the Karolinska Institute in Stockholm and co-author of what might be the biggest study on the link. The medication is available over the counter, so a lot of usage is not recorded in medical databases. This means researchers rely on self-reports, which can be unreliable.
Confounding factors are an even bigger problem. Women who take paracetamol in pregnancy are usually in poorer health than those who don’t, perhaps because they had an infection or an underlying condition. Any apparent link between acetaminophen and autism might therefore be explained by these other health factors rather than the drug itself.
evo ti drugi
https://pubmed.ncbi.nlm.nih.gov/40898607/
Another large, high-quality study from Japan including over 200,000 children — also using sibling comparisons and published this year, in 2025. — found no link between acetaminophen use in pregnancy and autism.
